Articles
Quality of medical prescriptions in diabetes and hypertension management in Kerala and its associated factors
Vijayakumar Krishnapillai, Sanjeev Nair, Anand T. N, Sreelal T. P, Biju Soman

BMC Public Health. 2020; 20: 193. Published online 2020 Feb 6. doi: 10.1186/s12889-020-8214-y

PMCID: PMC7006375


Associations of Fish Consumption with Risk of Cardiovascular Disease and Mortality among individuals with or without vascular disease From 58 Countries.

Mohan D, Mente A, Dehghan M, Rangarajan S, O'Donnell M, Hu W, Dagenais G, Wielgosz A, Lear S, Wei L, Diaz R, Avezum A, Lopez-Jaramillo P, Lanas F, Swaminathan S, Kaur M, Vijayakumar K, Mohan V, Gupta R, Szuba A, Iqbal R, Yusuf R, Mohammadifard N, Khatib R, Yusoff K, Gulec S, Rosengren A, Yusufali A, Wentzel-Viljoen E, Chifamba J, Dans A, Alhabib KF, Yeates K, Teo K, Gerstein HC, Yusuf S; PURE, ONTARGET, TRANSCEND, and ORIGIN investigators.JAMA Intern Med. 2021 May 1;181(5):631-649. doi: 10.1001/jamainternmed.2021.0036.PMID: 33683310

Cohort Profile : The PROLIFE study in Kerala, India

Chitakudam Raman Soman, SafrajShahulhameed, Vellapallil Raman Kutty, Krishna pillai Vijayakumar, Rajamohanan Kunjukrishnapillai, Kamalasanan Ajayan, Sarasan Sajikumar.. International Journal Epidemiology 2009;September 8;1-5 Int J Epidemiol  2011 Feb;40(1):10-4. doi: 10.1093/ije/dyp275. Epub 2009 Sep 8. PMID: 19740760

Modifiable risk factors, cardiovascular disease, and mortality in 155?722 individuals from 21 high-income, middle-income, and low-income countries
(PURE): a prospective cohort study. Yusuf S, Joseph P, Rangarajan S, Islam S, Mente A, Hystad P, Brauer M, Kutty VR, Gupta R, Wielgosz A, AlHabib KF, Dans A, Lopez-Jaramillo P, Avezum A, Lanas F, Oguz A, Kruger IM, Diaz R, Yusoff K, Mony P, Chifamba J, Yeates K, Kelishadi R, Yusufali A, Khatib R, Rahman O, Zatonska K, Iqbal R, Wei L, Bo H, Rosengren A, Kaur M, Mohan V, Lear SA, Teo KK, Leong D, O'Donnell M, McKee M, Dagenais G.Lancet. 2020 Mar 7;395(10226):795-808. doi: 10.1016/S0140-6736(19)32008-2.Epub 2019 Sep PMID: 31492503
The household economic burden of non-communicable diseases in 18 countries
Murphy A, Palafox B, Walli-Attaei M, Powell-Jackson T, Rangarajan S, Alhabib KF, Avezum AJ, Calik KBT, Chifamba J, Choudhury T, Dagenais G, Dans AL, Gupta R, Iqbal R, Kaur M, Kelishadi R, Khatib R, Kruger IM, Kutty VR, Lear SA, Li W, Lopez-Jaramillo P, Mohan V, Mony PK, Orlandini A, Rosengren A, Rosnah I, Seron P, Teo K, Tse LA, Tsolekile L, Wang Y, Wielgosz A, Yan R, Yeates KE, Yusoff K, Zatonska K, Hanson K, Yusuf S, McKee M.BMJ Glob Health. 2020 Feb 11;5(2):e002040. doi: 10.1136/bmjgh-2019-002040. eCollection 2020.PMID: 32133191
Household, Community, Sub-National and Country-level Predictors of Primary Cooking Fuel Switching in Nine Countries from the PURE Study
Shupler M, Hystad P, Gustafson P, Rangarajan S, Mushtaha M, Jayachtria KG, Mony PK, Mohan D, Kumar P, Lakshmi P, Sagar V, Gupta R, Mohan I, Nair S, Varma RP, Li W, Hu B, You K, Ncube T, Ncube B, Chifamba J, West N, Yeates K, Iqbal R, Khawaja R, Yusuf R, Khan A, Seron P, Lanas F, Lopez-Jaramillo P, Camacho PA, Puoane T, Yusuf S, Brauer M.Environ Res Lett. 2019 Aug;14(8):085006. doi: 10.1088/1748-9326/ab2d46. Epub 2019 Jul 29.PMID: 33777170
Comparison of Health-care Utilization Pattern and its Correlates among the Tribal and NonTribal Population of Kerala
Hisham Moosan, Antony Stanley, Aslesh Ottapura Prabhakaran, Krishnapillai Vijayakumar, A. K. Jayasree, Soumya Gopakumar Indian J Community Med. 2019 Oct; 44(Suppl 1): S57–S61. doi: 10.4103/ijcm.IJCM_46_19 PMCID: PMC6824181

Association of estimated sleep duration and naps with mortality and cardiovascular events: a study of 116?632 people from 21 countries
Wang C, Bangdiwala SI, Rangarajan S, Lear SA, AlHabib KF, Mohan V, Teo K, Poirier P, Tse LA, Liu Z, Rosengren A, Kumar R, Lopez-Jaramillo P, Yusoff K, Monsef N, Krishnapillai V, Ismail N, Seron P, Dans AL, Kruger L, Yeates K, Leach L, Yusuf R, Orlandini A, Wolyniec M, Bahonar A, Mohan I, Khatib R, Temizhan A, Li W, Yusuf S.Eur Heart J. 2019 May 21;40(20):1620-1629. doi: 10.1093/eurheartj/ehy695.PMID: 30517670 
Mortality and cardiovascular and respiratory morbidity in individuals with impaired FEV1 (PURE): an international, community-based cohort study.
Duong M, Islam S, Rangarajan S, Leong D, Kurmi O, Teo K, Killian K, Dagenais G, Lear S, Wielgosz A, Nair S, Mohan V, Mony P, Gupta R, Kumar R, Rahman O, Yusoff K, du Plessis JL, Igumbor EU, Chifamba J, Li W, Lu Y, Zhi F, Yan R, Iqbal R, Ismail N, Zatonska K, Karsidag K, Rosengren A, Bahonar A, Yusufali A, Lamelas PM, Avezum A, Lopez-Jaramillo P, Lanas F, O'Byrne PM, Yusuf S; PURE investigators.Lancet Glob Health. 2019 May;7(5):e613-e623. doi: 10.1016/S2214-109X(19)30070-1.PMID: 31000131
Health Effects of Household Solid Fuel Use: Findings from 11 Countries within the Prospective Urban and Rural Epidemiology Study
Hystad P, Duong M, Brauer M, Larkin A, Arku R, Kurmi OP, Fan WQ, Avezum A, Azam I, Chifamba J, Dans A, du Plessis JL, Gupta R, Kumar R, Lanas F, Liu Z, Lu Y, Lopez-Jaramillo P, Mony P, Mohan V, Mohan D, Nair S, Puoane T, Rahman O, Lap AT, Wang Y, Wei L, Yeates K, Rangarajan S, Teo K, Yusuf S; [on behalf of Prospective Urban and Rural Epidemiological (PURE) Study investigators].Environ Health Perspect. 2019 May;127(5):57003. doi: 10.1289/EHP3915.PMID: 31067132
Socioeconomic status and risk of cardiovascular disease in 20 low-income, middle-income, and high-income countries: the Prospective Urban Rural Epidemiologic (PURE) study
Annika Rosengren  1 , Andrew Smyth  2 , Sumathy Rangarajan  3 , Chinthanie Ramasundarahettige  3 , Shrikant I Bangdiwala  3 , Khalid F AlHabib  4 , Alvaro Avezum  5 , Kristina Bengtsson Boström  6 , Jephat Chifamba  7 , Sadi Gulec  8 , Rajeev Gupta  9 , Ehi U Igumbor  10 , Romaina Iqbal  11 , Norhassim Ismail  12 , Philip Joseph  3 , Manmeet Kaur  13 , Rasha Khatib  14 , Iolanthé M Kruger  15 , Pablo Lamelas  3 , Fernando Lanas  16 , Scott A Lear  17 , Wei Li  18 , Chuangshi Wang  18 , Deren Quiang  19 , Yang Wang  18 , Patricio Lopez-Jaramillo  20 , Noushin Mohammadifard  21 , Viswanathan Mohan  22 , Prem K Mony  23 , Paul Poirier  24 , Sarojiniamma Srilatha  25 , Andrzej Szuba  26 , Koon Teo  3 , Andreas Wielgosz  27 , Karen E Yeates  28 , Khalid Yusoff  29 , Rita Yusuf  30 , Afzalhusein H Yusufali  31 , Marjan W Attaei  3 , Martin McKee  32 , Salim Yusuf  3  Lancet Glob Health  2019 Jun;7(6):e748-e760.  doi: 10.1016/S2214-109X(19)30045-2. Epub 2019 Apr 23 PMID: 31028013  DOI: 10.1016/S2214-109X(19)30045-2 
Measuring childhood socioeconomic position in health research: Development and validation of childhood socioeconomic position questionnaire using mixed method approach
Uma Vadassery Sankar, V Raman Kutty, TN Anand Health  Promot  Perspect. 2019; 9(1): 40–49. Published online 2019 Jan 23. doi: 10.15171/hpp.2019.05 PMCID: PMC6377695
Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world.

Joseph P, Yusuf S, Lee SF, Ibrahim Q, Teo K, Rangarajan S, Gupta R, Rosengren A, Lear SA, Avezum A, Lopez-Jaramillo P, Gulec S, Yusufali A, Chifamba J, Lanas F, Kumar R, Mohammadifard N, Mohan V, Mony P, Kruger A, Liu X, Guo B, Zhao W, Yang Y, Pillai R, Diaz R, Krishnapillai A, Iqbal R, Yusuf R, Szuba A, Anand SS; PURE INVESTIGATORS.Heart. 2018 Apr;104(7):581-587. doi: 10.1136/heartjnl-2017-311609. Epub 2017 Oct 24.PMID: 29066611 

Availability and affordability of blood pressure-lowering medicines and the effect on blood pressure control in high-income, middle-income, and low-income countries: an analysis of the PURE study data

Attaei MW, Khatib R, McKee M, Lear S, Dagenais G, Igumbor EU, AlHabib KF, Kaur M, Kruger L, Teo K, Lanas F, Yusoff K, Oguz A, Gupta R, Yusufali AM, Bahonar A, Kutty R, Rosengren A, Mohan V, Avezum A, Yusuf R, Szuba A, Rangarajan S, Chow C, Yusuf S; PURE study investigators.Lancet Public Health. 2017 Sep;2(9):e411-e419. doi: 10.1016/S2468-2667(17)30141-X. Epub 2017 Sep 5.PMID: 29253412

The effect of physical activity on mortality and cardiovascular disease in 130?000 people from 17 high-income, middle-income, and low-income countries: the PURE study
Lear SA, Hu W, Rangarajan S, Gasevic D, Leong D, Iqbal R, Casanova A, Swaminathan S, Anjana RM, Kumar R, Rosengren A, Wei L, Yang W, Chuangshi W, Huaxing L, Nair S, Diaz R, Swidon H, Gupta R, Mohammadifard N, Lopez-Jaramillo P, Oguz A, Zatonska K, Seron P, Avezum A, Poirier P, Teo K, Yusuf S.Lancet. 2017 Dec 16;390(10113):2643-2654. doi: 10.1016/S0140-6736(17)31634-3. Epub 2017 Sep 21.PMID: 28943267 
Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study
Miller V, Mente A, Dehghan M, Rangarajan S, Zhang X, Swaminathan S, Dagenais G, Gupta R, Mohan V, Lear S, Bangdiwala SI, Schutte AE, Wentzel-Viljoen E, Avezum A, Altuntas Y, Yusoff K, Ismail N, Peer N, Chifamba J, Diaz R, Rahman O, Mohammadifard N, Lana F, Zatonska K, Wielgosz A, Yusufali A, Iqbal R, Lopez-Jaramillo P, Khatib R, Rosengren A, Kutty VR, Li W, Liu J, Liu X, Yin L, Teo K, Anand S, Yusuf S; Prospective Urban Rural Epidemiology (PURE) study investigators.Lancet. 2017 Nov 4;390(10107):2037-2049. doi: 10.1016/S0140-6736(17)32253-5. Epub 2017 Aug 29.PMID: 28864331
Association of Household Wealth Index, Educational Status, and Social Capital with Hypertension Awareness, Treatment, and Control in South Asia
Gupta R, Kaur M, Islam S, Mohan V, Mony P, Kumar R, Kutty VR, Iqbal R, Rahman O, Deepa M, Antony J, Vijaykumar K, Kazmi K, Yusuf R, Mohan I, Panwar RB, Rangarajan S, Yusuf S.Am J Hypertens. 2017 Apr 1;30(4):373-381. doi: 10.1093/ajh/hpw169.PMID: 28096145
Tobacco control environment: cross-sectional survey of policy implementation, social unacceptability, knowledge of tobacco health harms and relationship to quit ratio in 17 low-income, middle-income and high-income countries
Chow CK, Corsi DJ, Gilmore AB, Kruger A, Igumbor E, Chifamba J, Yang W, Wei L, Iqbal R, Mony P, Gupta R, Vijayakumar K, Mohan V, Kumar R, Rahman O, Yusoff K, Ismail N, Zatonska K, Altuntas Y, Rosengren A, Bahonar A, Yusufali A, Dagenais G, Lear S, Diaz R, Avezum A, Lopez-Jaramillo P, Lanas F, Rangarajan S, Teo K, McKee M, Yusuf S.BMJ Open. 2017 Mar 31;7(3):e013817. doi: 10.1136/bmjopen-2016-013817.PMID: 28363924
Effects of bidi smoking on all-cause mortality and cardiorespiratory outcomes in men from south Asia: an observational community-based substudy of the Prospective Urban Rural Epidemiology Study (PURE).
Duong M, Rangarajan S, Zhang X, Killian K, Mony P, Swaminathan S, Bharathi AV, Nair S, Vijayakumar K, Mohan I, Gupta R, Mohan D, Rani S, Mohan V, Iqbal R, Kazmi K, Rahman O, Yusuf R, Pinnaka LV, Kumar R, O'Byrne P, Yusuf S.Lancet Glob Health. 2017 Feb;5(2):e168-e176. doi: 10.1016/S2214-109X(17)30004-9.PMID: 28104186
The environmental profile of a community’s health: a cross-sectional study on tobacco marketing in 16 countries
Emily Savell, Anna B Gilmore, Michelle Sims, Prem K Mony, Teo Koon, Khalid Yusoff, Scott A Lear, Pamela Seron, Noorhassim Ismail, K Burcu Tumerdem Calik, Annika Rosengren, Ahmad Bahonar, Rajesh Kumar, Krishnapillai Vijayakumar, Annamarie Kruger, Hany Swidan, Rajeev Gupta, Ehimario Igumbor, Asad Afridi, Omar Rahman, Jephat Chifamba, Katarzyna Zatonska, V Mohan, Deepa Mohan, Patricio Lopez-Jaramillo, Alvaro Avezum, Paul Poirier, Andres Orlandini, Wei Li, Martin McKee, Sumathy Rangarajan, Salim Yusuf, Clara K Chow
Bull World Health Organ. 2015 Dec 1; 93(12): 851–861G. Published online 2015 Dec 1. doi: 10.2471/BLT.15.155846 PMCID: PMC4669733

Risk of mortality among alcohol using adult males in a population-based cohort in Kerala,India: PROFILE study
Krishnapillai Vijayakumar, Rekha Rachel Philip1, Shrinivasa ,Basavegowdanadoddi,Marinaik, Pratheeksha Giridharan3, Sairu Philip4, Biju George5 International Journal of Medicine and Public Health Jan- March 2015 Vol 5, Issue 1
The association between ownership of common household devices and obesity and diabetes in high, middle and low income countries
Scott A. Lear, Koon Teo, Danijela Gasevic, Xiaohe Zhang, Paul P. Poirier, Sumathy Rangarajan, Pamela Seron, Roya Kelishadi, Azmi Mohd Tamil, Annamarie Kruger, Romaina Iqbal, Hani Swidan, Diego Gómez-Arbeláez, Rita Yusuf, Jephat Chifamba, V. Raman Kutty, Kubilay Karsidag, Rajesh Kumar, Wei Li, Andrzej Szuba, Alvaro Avezum, Rafael Diaz, Sonia S. Anand, Annika Rosengren, Salim Yusuf  CMAJ. 2014 Mar 4; 186(4): 258–266. doi: 10.1503/cmaj.131090 Correction in:  CMAJ. 2014 Apr 1; 186(6): 453. PMCID: PMC3940572
Cardiovascular Risk and Events in 17 Low-, Middle-, and High-Income Countries.
S. Yusuf, S. Rangarajan, K. Teo, S. Islam, W. Li, L. Liu, J. Bo, Q. Lou, F. Lu, T. Liu, L. Yu, S. Zhang, P. Mony, S. Swaminathan, V. Mohan, R. Gupta, R. Kumar, K. Vijayakumar, S. Lear, S. Anand, A. Wielgosz, R. Diaz, A. Avezum, P. Lopez-Jaramillo, F. Lanas, K. Yusoff, N. Ismail, R. Iqbal, O. Rahman,A. Rosengren, A. Yusufali, R. Kelishadi, A. Kruger, T. Puoane, A. Szuba,J. Chifamba, A. Oguz, M. McQueen, M. McKee, and G. Dagenais, for the PURE Investigators New England Journal of Medicine 2014;371:818-27 DOI : 10.1056/NEJMoa1311890
Global differences in lung function by region (PURE): an international community based, prospective study; Lancet Respiratory Medicine 09/2013; 1(8):599-609 DO:101016/S2213-2600(13) 70
Dr. My Linh Duong MBBS, Shofiqul Islam MSc, SumathyRangarajan MSc, Prof Koon Teo PhD, Prof Paul O' Byrne MD, Prof. Holger J Schünemann PhD, Ehimario I gumbor  PhD,  Jephatifamba PhD, Prof. Lisheng Liu MD, Prof Wei Li PhD, Tengku Ismail MD, Kiruba Shankar MD, Muhammad Shahid MPH, KrishnapillaiVijayakumar MD, Rita Yusuf PhD, KatarzynaZatonska PhD, Prof AytekinOguz MD, Prof Annika Rosengren MD, Hossain Heidari MD, Wael Al Mahmeed MD, Rafael Diaz MD, Gustavo Oliveira PhD, Prof. Patricio Lopez Jaramillo PhD, PamelaSeron MD, Prof. Kieran Killian MD, Prof Salim Yusuf DPhil for. The Lancet Respiratory Medicine, Volume 1, Issue 8, Pages 599 - 609, October 2013 doi:10.1016/S2213-2600(13)70164-4 Published Online: 10 September 2013
Prevalence of a healthy lifestyle among individuals with cardiovascular disease in high-, middle- and low-income countries: The Prospective Urban Rural Epidemiology (PURE) study
Teo K, Lear S, Islam S, Mony P, Dehghan M, Li W, Rosengren A, Lopez-Jaramillo P, Diaz R, Oliveira G, Miskan M, Rangarajan S, Iqbal R, Ilow R, Puone T, Bahonar A, Gulec S, Darwish EA, Lanas F, Vijaykumar K, Rahman O, Chifamba J, Hou Y, Li N, Yusuf S: PURE Investigators- ”. (PMID: 23592106)  JAMA: the Journal of the American Medical Association , April 17 [2013, 309(15):1613-1621]
Cohorts in chronic disease research: experiences from the PRO-LIFE cohort, Varkala, South India
V Raman Kutty BMC Proc. 2013; 7(Suppl 5): O7. Published online 2013 Aug 30. doi: 10.1186/1753-6561-7-S5-O7 PMCID: PMC3892173
Use of secondary prevention of drugs for cardiovascular disease in the community of high income, middle income and low income countries (PURE Study): a prospective epidemiological l survey
“ www.lancet.com.  Published online August 28, 2011.
Salim Yusuf  1 , Shofiqul Islam, Clara K Chow, Sumathy Rangarajan, Gilles Dagenais, Rafael Diaz, Rajeev Gupta, Roya Kelishadi, Romaina Iqbal, Alvaro Avezum, Annamarie Kruger, Raman Kutty, Fernando Lanas, Liu Lisheng, Li Wei, Patricio Lopez-Jaramillo, Aytekin Oguz, Omar Rahman, Hany Swidan, Khalid Yusoff, Witold Zatonski, Annika Rosengren, Koon K Teo, Prospective Urban Rural Epidemiology (PURE) Study Investigators PMID: 21872920 Lancet  2011 Oct 1;378(9798):1231-43.  doi: 10.1016/S0140-6736(11)61215-4. Epub 2011 Aug 26. 

Socioeconomic Position and Prevalence of Self-Reported Diabetes in Rural Kerala
Shahulhameed Safraj, T S Anish, KrishnapillaVijayakumar, Vellapallil Raman Kutty, Chittakudam Raman Soman . India: Results from the PROLIFE Study. Asia Pac J Public Health. 2010; Dec 15.PMID: 21159691
All cause of Mortality and Cardiovascular Mortality in Kerala State of India : Results From a 5 Year Follow up of 161942 Rural Community Dwelling Adults. Results from PROLIFE Study
C R Soman, V.R. Kutty, S. Safraj, K Vijayakumar, K. Rajamohanan,K. Ajayan..Asia Pac J Public Health. 2010; May 10 XX (X)1-8
Suicide in South India: A community-based study in Kerala

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Cohort Profile : The PROLIFE study in Kerala, India
Chitakudam Raman Soman, SafrajShahulhameed, Vellapallil Raman Kutty, Krishna pillai Vijayakumar, Rajamohanan Kunjukrishnapillai, Kamalasanan Ajayan, Sarasan Sajikumar.. International Journal Epidemiology 2009;September 8;1-5 Int J Epidemiol  2011 Feb;40(1):10-4. doi: 10.1093/ije/dyp275. Epub 2009 Sep 8. PMID: 19740760